Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Southwest Coast Florida hotels

A modern hotel lobby with a reception desk, seating area, and a dining section.

1. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor

Brian

includes taxes & fees

13 Nov - 14 Nov

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

2. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor

Bruce

includes taxes & fees

22 Nov - 23 Nov

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

3. Best Western Fort Myers Inn & Suites

Fort Myers

Azael

includes taxes & fees

30 Nov - 1 Dec

A modern kitchen area with a breakfast bar, fruit display, and a chalkboard menu.

4. Hampton Inn Fort Myers Downtown

Fort Myers River District

Donald

includes taxes & fees

25 Nov - 26 Nov

A hotel room with a bed, a desk, a chair, and a small table.

5. SpringHill Suites by Marriott Fort Myers Airport

Daniels Corridor

Jon B.

includes taxes & fees

22 Nov - 23 Nov

A Drury Inn & Suites hotel with a parking lot full of cars.

6. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes

Giselia Dos Santos

includes taxes & fees

1 Dec - 2 Dec

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

7. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor

Merlin

includes taxes & fees

22 Nov - 23 Nov

A swimming pool with a stone wall and palm trees, surrounded by a building with large windows and outdoor seating.

8. Doubletree by Hilton Fort Myers at Bell Tower Shops

Villas

James

includes taxes & fees

29 Nov - 30 Nov

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

9. Comfort Suites Fort Myers East I-75

Fort Myers

Eloan

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio with a barbecue area, seating, and string lights.

10. Homewood Suites by Hilton Fort Myers Airport/FGCU

Miromar Lakes

Leo

includes taxes & fees

29 Nov - 30 Nov

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

11. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Fort Myers Beach

Kimberly

includes taxes & fees

16 Nov - 17 Nov

A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

12. Hampton Inn & Suites Fort Myers - Colonial Blvd

Fort Myers

Luis

includes taxes & fees

29 Nov - 30 Nov

A Comfort Inn & Suites hotel with a covered entrance, palm trees, and a well-lit facade.

13. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor

Frank

includes taxes & fees

30 Nov - 1 Dec

A large, clear swimming pool with multiple lounge areas and palm trees.

14. Margaritaville Beach Resort Fort Myers

Fort Myers Beach

Lance

includes taxes & fees

29 Nov - 30 Nov

15. Hyatt Place Fort Myers/at The Forum

The Forum

Cornel

includes taxes & fees

22 Nov - 23 Nov

A balcony with wicker furniture, a view of a beach, and a clear sky.

16. Lani Kai Beachfront Resort

Fort Myers Beach

yeny

includes taxes & fees

3 Dec - 4 Dec

An outdoor patio with a fire pit, green chairs, a red umbrella, and a bar area.

17. Home2 Suites by Hilton Fort Myers Colonial Blvd

Fort Myers

Julio

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio area with a stone fire pit, seating, and string lights.

18. SpringHill Suites by Marriott Fort Myers Estero

Estero

Nail

includes taxes & fees

15 Nov - 16 Nov

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

19. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor

Isaura

includes taxes & fees

6 Dec - 7 Dec

A hotel with a covered entrance, palm trees, and a well-maintained garden.

20. Homewood Suites by Hilton - Fort Myers

Villas

Anne

includes taxes & fees

29 Nov - 30 Nov

View all properties

Holiday Rentals in Southwest Coast Florida

Aparthotel

A balcony with a TV, a chair, and a view of a beach with a pier.

Edison Beach House

Fort Myers Beach

"Great stay."

Aparthotel

A beach with a thatched-roof structure, palm trees, and a view of the sea.

The Suites at Fishermen’s Village

Punta Gorda Isles

"Great place to stay but comes with a price."

Aparthotel

A modern hotel room with a kitchenette, a bed, a seating area, and a wardrobe.

StudioRes by Marriott Fort Myers Airport

Fort Myers

"Location was great."

Apartment

A swimming pool with lounge chairs and a building with a sloped roof in the background.

Landing Apartments Fort Myers near Eastwood Village

Fort Myers

"Amazing , safe and beautiful place to stay . I was there for over 3 weeks and it’s local to many great locations , quiet and safe and over all highly recommend."

Villa

A compact kitchen with a built-in seating area, a refrigerator, and a ceiling fan.

Matlacha Tiny Village

Matlacha

"So cute and clean nice dock to sit and relax or fish. Kayaks available to use free as well with life jackets paddles, etc. well equipped rental we can’t wait to go again! Great communication with hosts."

Aparthotel

A modern kitchen with a large island, a dining area with chairs, and a view of the outdoors.

Sanibel Siesta on the Beach

Mid Island

"Great location and close to beach. Rooms nice and it had everything you needed for the beach. Pool wonderful"

Apartment

A modern building with a white exterior, a brick gable, and a palm tree in the foreground.

Pelican Post at Anna Maria Island Inn

Bradenton Beach

"Location was perfect"

See all holiday rentals

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Stay near popular Southwest Coast Florida attractions

A lifeguard tower with an American flag, a green flag, and a signboard on a beach with people sunbathing and umbrellas.

Siesta Key Beach

9.6/10 (4,113 reviews)

The soft, white sand on Siesta Key’s award-winning family-friendly beach is perfect for relaxing under a sun umbrella and taking part in a game of volleyball.

See properties

Learn more about Southwest Coast Florida

Amazing beaches, island views and top sights from Key West Express to Siesta Key Beach—discover Southwest Coast Florida, a destination also famous for its live music scene.

See all hotels in Southwest Coast Florida

A sunset over a beach with a pier and people walking on the sand.

Top Southwest Coast Florida Hotel Reviews

Recent Reviews in Southwest Coast Florida

Kompose Boutique Hotel

8/10 Good

"Everything was great"

Carlisle Inn

10/10 Excellent

"Hôtel est d'une propreté exceptionnelle, tout est propre lobby, ascenseur,passage, les chambres ainsi que la terrasse et piscine extérieur. Un des Hôtel les plus propre que j'ai fréquenté ! Les deux seuls petits points négatifs pour moi, le déjeuner est " basics " comme a bien des endroits d'ailleurs mais par contre la salle a manger est super propre et j'ai trouvé le matelas un peu mou a mon goûts mais certain vont adoré. À recommandé sans hésiter !"

Golden Host Resort - Sarasota

10/10 Excellent

"We loved our stay! The Tiki Bar was busy our first night but fortunately did not hear a thing since further away on the property. Only on Halloween night did someone accidentally knock on our door, otherwise we had an easy check in and check out. We also had a clean room with all the amenities available. We loved how unique the property, rooms and Tiki Bar were."

More cheap accommodation in Southwest Coast Florida

Days Inn by Wyndham Bradenton I-75

644 67th Street Cir E Bradenton FL

AU$75

22 Nov - 23 Nov

includes taxes & fees

6/10 (348 reviews)

Explore a world of travel with Expedia

Book Hotels in Southwest Coast Florida on Expedia.com

Search Southwest Coast Florida hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southwest Coast Florida

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Southwest Coast Florida hotels

1. Holiday Inn Express & Suites Fort Myers Airport by IHG

2. Hampton Inn Fort Myers-Airport & I-75

3. Best Western Fort Myers Inn & Suites

4. Hampton Inn Fort Myers Downtown

5. SpringHill Suites by Marriott Fort Myers Airport

6. Drury Inn & Suites Fort Myers Airport FGCU

7. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

8. Doubletree by Hilton Fort Myers at Bell Tower Shops

9. Comfort Suites Fort Myers East I-75

10. Homewood Suites by Hilton Fort Myers Airport/FGCU

11. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

12. Hampton Inn & Suites Fort Myers - Colonial Blvd

13. Comfort Inn & Suites Fort Myers Airport

14. Margaritaville Beach Resort Fort Myers

15. Hyatt Place Fort Myers/at The Forum

16. Lani Kai Beachfront Resort

17. Home2 Suites by Hilton Fort Myers Colonial Blvd

18. SpringHill Suites by Marriott Fort Myers Estero

19. Extended Stay America Premier Suites - Fort Myers - Airport

20. Homewood Suites by Hilton - Fort Myers

Holiday Rentals in Southwest Coast Florida

Edison Beach House

Stay near popular Southwest Coast Florida attractions

Siesta Key Beach

Learn more about Southwest Coast Florida

Top Southwest Coast Florida Hotel Reviews

Recent Reviews in Southwest Coast Florida

Kompose Boutique Hotel

More cheap accommodation in Southwest Coast Florida

Days Inn by Wyndham Bradenton I-75

Explore a world of travel with Expedia

Go further with the Expedia app